Joint cartilage lesions are seen as a major musculoskeletal system problem that have a negative effect on quality of life, and are observed at increasing rates. Cartilage tissue covering the joint surface has no neurological, vascular or lymphatic organization. Therefore, the intrinsic healing potential is limited. Despite current advances in technology and the accumulated knowledge of basic sciences, there are still problems remaining in the treatment of cartilage injuries. , the current treatment options are abrasion chondroplasty, bone marrow stimulation technique (microfracture and drilling), mosaicplasty – osteochondral autograft transfer system (OATS), osteochondral allografts, and cell-based treatment methods such as autologous chondrocyte implantation (ACI) and matrix-induced autologous chondrocyte implantation (MACI).

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